Clinical-grade skincare brand IOPE is officially entering the North American market, joining Sephora—the world’s largest beauty retailer—across its online and in-store channels.
Beginning in March, IOPE will be available at Sephora stores across the United States and on its online platform, introducing its “Clinical Grade” skincare. Through its partnership with Sephora, a leading global beauty retailer, IOPE aims to establish itself in North America as a technology-driven, high-performance anti-aging brand. It plans to expand into the global anti-aging market, starting with North America.
IOPE’s North American launch lineup will be led by the “XMD Stem3 Clinical Recovery Serum” and “Retinol Retiject™ Serum.” Human application tests comparing the products with specialized treatments demonstrated dermatologist-level[2] efficacy.
The “XMD Stem3 Clinical Recovery Serum” contains a high concentration of 92.3%[3] PDRN H.A.™ complex and has been shown to improve skin hydration and pore tightening[4]. The “Retinol Retiject™ Serum,” which delivers retinol through 3 million spicules, has been shown to improve skin firmness, wrinkles, and pores after just one use.
The lineup also includes the “Retinol Super Bounce Serum,” formulated to boost collagen production by improving skin penetration; the “Vitamin C Expert 40% Mask Concentrate,” containing the highest concentration of pure vitamin C ever used by Amorepacific; and the “PDRN Caffeine Shot Ampoule,” designed to repair both deep and surface layers of the skin. With this high-performance anti-aging lineup, IOPE is targeting North America’s premium skincare market.
“Drawing on 30 years of retinol and skin science research, IOPE has built a distinctive competitive edge by offering high-performance anti-aging solutions,” said Jong-ha Kim, executive vice president of Amorepacific’s Active Beauty Unit. “Our Sephora launch will help us strengthen IOPE’s position in North America as a Clinical Grade[1] skincare brand.”
Launched in 1996, IOPE has led the anti-aging market by successfully stabilizing retinol in skincare products. Over the past 30 years, the brand has advanced its anti-aging technology through accumulated skin science research, earning 26 patents and publishing 43 research papers to date. More recently, it has expanded into Clinical Grade[1] skincare, offering high-performance solutions with proven skin benefits.
[1] Applies to human efficacy testing only
[2] Refers to skincare for healthy skin
[3] PDRN: 0.015%
[4] Results for pore area after four weeks of use; refers to a temporary pore-tightening effect
Questions about this story?
AI answers only from this article and related ones.
Answered from ten years of our reporting. Check legal and tax questions with a professional.


